The Results
Dramatic results were seen within just 3 months of the trial. The
children in the active group
supplementing with fatty acids saw
significant improvements in reading (9.5 months), spelling
(6.5
months) and behaviour, compared to the placebo group where no
overall improvement
was made.
During the 3-6 month period when the placebo group crossed over
to fatty acid supplement-
ation, considerable improvements were
shown in the same areas, with an average reading
gain of 13.5
months and an average spelling gain at over 6 months.
The active group that
continued with fatty acid
supplementation showed further signs of progress or maintained
their improvement.
At the start of the trial, all of the school children were a year
behind their chronological age
for reading and spelling,
but after the trial, the active group who had been on fatty acids
throughout the trial made spelling and reading gains over and
above their chronological age.
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Reading and Spelling
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Performance
€¢ During the
first 3 months the average gain for children taking
fatty acids was 9.5 months for reading and 6.5 months for
spelling. This was a highly significant improvement compared
to the control group gains for reading (p < 0.004) and
spelling (p < 0.001).
.
€¢ Between 3-6 months, children switching from placebo to
capsules made an average reading gain of 13.5 months and
over 6 months for spelling. The fish oil group who had been on
fatty acids from the beginning of the trial continued to make
reading and spelling gains over and above what would be
expected for their chronological
ages. |
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Fatty Acids vs Stimulant
Medication
The treatment effect size on Conner's ADHD index rating was
0.55 in the first 3 months, and over 0.70 over the 6 months.
This is comparable to the average effect size for stimulant
medication: 0.78.
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Comparable treatment effects on Conners' ADHD Index
Rating
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ADHD
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Clinical range of ADHD
€¢ At the
start of the trial, the percentage of children within the
clinical range of an ADHD diagnosis was set at 32% for the
fatty acid group and 31% for the placebo group.
€¢ After 3 months supplementation, the percentage of
children with the clincical range of an ADHD diagnosis reduced
to 18% for the fatty acid group, whereas this only dropped 1 %
for the
placebo.
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| Behaviour Raw Score
Total
A raw score was calculated from the
teacher rating form that assessed each child's behaviour.
After 3 months there was a highly significant reduction
(p < 0.0001) seen in the active supplement group,
compared to those on placebo, in this behavioural
score. The fatty acid group reduced from an average
score of 74.7 to 58.1., whereas the before and after
treatment scores for the placebo group were 69.5 and
67.9.
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DSM-IV Total
ADHD
The active group saw significantly
reduced (p < 0.00001) teacher ratings on
the Conners' DSM ADHD global scale after 3 months,
compared with the placebo group. The placebo group
saw similar improvements on this scale after crossing
over to the active oils for the 3-6 month
period of the
trial.
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DSM-IV
Hyperactive-Impulsive
After just 3 months children on the
active supplement saw a significant reduction on the rating
scale of Hyperactive-Impulsive behaviour, compared to those on
placebo (p < 0.00001). Further reductions were
seen in the 3-6 month period of the
study.
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